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. Author manuscript; available in PMC: 2019 Dec 23.
Published in final edited form as: J Hypertens. 2018 May;36(5):1094–1103. doi: 10.1097/HJH.0000000000001680

TABLE 2.

Enriched biological process gene ontology terms

Biological process GO terma Genes P value P value corrected for multiple testing
Regulation of blood pressure 47 1.20E – 59 2.70E – 56
Blood circulation 55 3.50E – 57 3.90E – 54
Circulatory system process 55 3.50E – 57 3.90E – 54
Regulation of systemic arterial blood pressure 27 9.90E – 42 7.30E – 39
Regulation of system process 52 2.10E – 40 1.20E – 37
Chemical homeostasis 61 6.20E – 39 2.70E – 36
Regulation of systemic arterial blood pressure mediated by a chemical signal 23 4.90E – 37 1.80E – 34
Homeostatic process 66 3.00E – 34 9.40E – 32
Vascular process in the circulatory system 25 8.50E – 30 2.10E – 27
Regulation of systemic arterial blood pressure by hormones 18 2.10E – 29 4.60E – 27
Regulation of vasoconstriction 21 4.70E – 29 8.60E – 27

DAVID, Database for Annotation Visualization and Integrated Discovery; GO, gene ontology; HTNGL, hypertension gene list.

a

The most enriched GO biological processes in the HTNGL gene list as derived using DAVID.