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. Author manuscript; available in PMC: 2020 Dec 11.
Published in final edited form as: Metallomics. 2019 Dec 11;11(12):2020–2032. doi: 10.1039/c9mt00228f

Figure 7. Fluconazole depletes EPR-detectable Fe and increases EPR-detectable Mn.

Figure 7.

(a) Cu supplementation alone (blue trace) does not impact the EPR signal at g = 4.3 relative to the untreated control cells (green trace). (b) Treatment with Flu (red trace) or Flu + Cu (purple trace) substantially attenuates the g = 4.3 signal. The signals in the g = 2 region are taken to be from Mn. Conditions: [Flu] = 10 µM, [CuSO4] = 10 µM. Cells were treated for 6 h in YPD before analysis.