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. 2019 Nov 22;5(11):e000316. doi: 10.1099/mgen.0.000316

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© 2019 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License.

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Fig. 1. — Frequency of antibiotic resistance by emm type and association with invasive disease in GAS strains from Houston, TX, USA. (a) Total number of isolates by emm type (left y-axis) and frequency of any antibiotic resistance (red bars). Only those emm types with at least 10 observations are indicated. Cumulative frequency of resistance is indicated by the red line (right y-axis). (b) Invasive index versus frequency of antibiotic resistance by emm type in the Houston GAS strains. Cumulative invasive indices and resistance ratios (see Methods and Table S1) are indicated between low-frequency (blue shaded circle) and high-frequency (red shaded circle) resistant emm types (Fisher’s exact test). emm92 GAS strains are not shown as no pharyngeal isolates were identified in the Houston GAS collection for calculation of the invasive index.