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Observed QARS variants in a schematic illustration; NTD involved in RNA binding, CATD, and ABD. Novel variants (full arrows), published variants (empty arrows, gray). New and published QARS variants are listed in table e-3 (links.lww.com/NXG/A197). Protein Ref Seq NP_005042.1. ABD = anticodon-binding domain; CATD = catalytic domain; NTD = N-terminal domain.
