Table 1.
Clinical Characteristics of 94 Patients with Synchronous Krukenberg Tumors
| Variable | Metastasectomy n=57 (%) | Nonmetastasectomy n=37 (%) | p value |
|---|---|---|---|
| Age | 0.598 | ||
| ≥45 | 17 (29.8) | 13 (35.1) | |
| <45 | 40 (70.2) | 24 (64.9) | |
| Year of diagnosis | 0.262 | ||
| 2006–2008 | 14 (24.6) | 5 (13.5) | |
| 2009–2012 | 22 (38.6) | 20 (54.1) | |
| 2013–2016 | 21 (36.8) | 12 (32.4) | |
| Menstrual status | 0.095 | ||
| Premenopausal | 39 (68.4) | 31 (83.8) | |
| Postmenopausal | 18 (31.6) | 6 (16.2) | |
| Tumor location | |||
| Upper 1/3 | 6 (10.5) | 4 (10.8) | 1.000 |
| Middle 1/3 | 19 (33.3) | 12 (32.4) | |
| Lower 1/3 | 22 (38.6) | 14 (37.8) | |
| Whole stomach | 10 (17.5) | 7 (18.9) | |
| Linitis plastica | 1.000 | ||
| Yes | 6 (10.5) | 4 (10.8) | |
| No | 51 (89.5) | 33 (89.2) | |
| Signet-ring cells | 0.773 | ||
| Yes | 31 (54.4) | 19 (51.4) | |
| No | 26 (45.6) | 18 (48.6) | |
| Laterality | 0.185 | ||
| Bilateral | 48 (84.2) | 27 (73.0) | |
| Unilateral | 9 (15.8) | 10 (27.0) | |
| Tumor size (cm) | 8.7±4.5 | 6.2±3.0 | 0.031 |
| Pathologic differentiation | 0.943 | ||
| Differentiated | 8 (14.0) | 5 (13.5) | |
| Undifferentiated | 49 (86.0) | 32 (86.5) | |
| Other types of metastasis | 37 (64.9) | 31 (83.8) | 0.046 |
| Peritoneum | 37 (64.9) | 28 (75.7) | 0.270 |
| Liver | 0 | 3 | |
| Supraclavicular lymph nodes | 0 | 6 | |
| Bone | 1 | 2 | |
| Lung | 2 | 2 | |
| Other | 0 | 2 | |
| Ascites | 0.089 | ||
| Yes | 30 (52.6) | 26 (70.3) | |
| No | 27 (47.4) | 11 (29.7) | |
| Gastrectomy | <0.001 | ||
| Yes | 28 (49.1) | 0 (0) | |
| No | 29 (50.9) | 37 (100) | |
| Distal gastrectomy | 17 | - | |
| Proximal gastrectomy | 3 | - | |
| Total gastrectomy | 8 | - | |
| Systemic chemotherapy | 0.020 | ||
| Yes | 49 (86.0) | 37 (100) | |
| No | 8 (14.0) | 0 (0) |