Table 3.
Detection Precision (%) ≥ 40µm MCTS | Detection Precision (%) ≥ 60µm MCTS | |
---|---|---|
Control | 100 | 77.3 |
AOL 5µg/mL | 96.7 | 67.0 |
AOL 10µg/mL | 87.7 | 48.2 |
AOL 25µg/mL | 78.8 | 11.5 |
UEA-1 5µg/mL | 100 | 70.7 |
UEA-1 10µg/mL | 100 | 82.5 |
UEA-1 25µg/mL | 100 | 80.7 |
Avg. Detection Precision (%) | 95.6 | 63.6 |
Notes: Detection precision of DU145 MCTS treated with 50µM cyclo-RGDfK(TPP) with AOL or UEA-1 lectins at different concentrations. Overall detection precision of using ≥ 40µm vs ≥ 60µm as a diameter threshold for the fucose lectin inhibition of spheroid formation.