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. 2019 Dec 19;12:11305–11311. doi: 10.2147/OTT.S228301

Figure 4.

Figure 4

Fluctuation of serum NSE and pro-GRP. (A) The fluctuation of serum NSE (12.26 ng/mL at baseline, 38.48 ng/mL, at the time of resistant to AZD9291,45.35 ng/mL at time of resistant to EC after 4 cycles, 17.71 ng/mL at time of response to IO after 2 cycles, 52.9 ng/mL at time of resistant to IO after 4 cycles, 18.17 ng/mL at time of response to abraxane after 4 cycles, 25.09 ng/mL at time of resistant to abraxane after 4 cycles,18.93 ng/mL at time of treatment of apatinib after 6 weeks). (B) The fluctuation of serum pro-GRP (22.35 pg/mL at time of response to IO after 2 cycle, 27.94 pg/mL at time of resistant to IO after 4 cycles, 21.05 pg/mL at time of response to abraxane after 4 cycles, 17.79 pg/mL at time of resistant to abraxane after 4 cycles, 18.94 pg/mL at time of treatment of apatinib after 6 weeks).