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. 2019 Dec 19;12:11241–11254. doi: 10.2147/OTT.S220621

Figure 3.

Figure 3

MiR-27a-3p enhances the angiogenesis of pancreatic carcinoma cells in vitro. (A) The tube formation capacities of HEVECs were observed after transfected miR-27a-3p mimic or mimic scrambled control. (B) MiR-27a-3p knockdown significantly decreased tube formation capability compared with inhibitor scrambled control group. (C) The protein expression of VEGFA and VEGFR2 in AsPC-1 and Panc-1 cells was detected by Western blotting analysis after overexpression of miR-27a-3p. GAPDH was used as an internal control. (D) MiR-27a-3p knockdown downregulated the VEGFA and VEGFR2 protein expression in pancreatic carcinoma cells. *P<0.05.