Table 3. HRs (95% CI) of mortality outcomes according to dipstick proteinuria categories in patients aged 70 years or older.
| Proteinuria (dipstick) | |||||
|---|---|---|---|---|---|
| negative/trace | 1+ | 2+ | ≥3+ | P for trend | |
| (n = 36) | (n = 88) | (n = 233) | (n = 339) | (n = 696) | |
| All-cause mortality (262 deaths) | 24 deaths | 40 deaths | 89 deaths | 109 deaths | |
| Model 1 | 3.68 (2.36–5.73) ** | 1.55 (1.08–2.23) * | 1.26 (0.95–1.66) | ref | <0.001 |
| Model 2 | 3.54 (2.27–5.52) ** | 1.54 (1.07–2.22) * | 1.27 (0.96–1.68) | ref | <0.001 |
| Model 3 | 3.37 (2.15–5.30) ** | 1.45 (1.00–2.10) * | 1.26 (0.95–1.68) | ref | <0.001 |
| Model 4 | 2.84 (1.70–4.76) ** | 1.39 (0.95–2.05) | 1.14 (0.84–1.55) | ref | 0.001 |
| CVD mortality (86 deaths) | 10 deaths | 15 deaths | 31 deaths | 30 deaths | |
| Model 1 | 5.66 (2.76–11.61) ** | 2.14 (1.15–3.98) * | 1.61 (0.97–2.65) | ref | <0.001 |
| Model 2 | 5.56 (2.70–11.43) ** | 2.15 (1.15–3.99) * | 1.62 (0.98–2.67) | ref | <0.001 |
| Model 3 | 4.92 (2.36–10.28) ** | 2.03 (1.07–3.86) * | 1.64 (0.99–2.72) | ref | <0.001 |
| Model 4 | 2.97 (1.28–6.87) * | 1.65 (0.84–3.21) | 1.27 (0.74–2.19) | ref | 0.01 |
| non-CVD mortality (176 deaths) | 14 deaths | 25 deaths | 58 deaths | 79 deaths | |
| Model 1 | 2.94 (1.66–5.20) ** | 1.33 (0.85–2.09) | 1.13 (0.80–1.58) | ref | 0.003 |
| Model 2 | 2.81 (1.58–4.97) ** | 1.31 (0.84–2.06) | 1.14 (0.81–1.60) | ref | 0.004 |
| Model 3 | 2.76 (1.55–4.94) ** | 1.24 (0.78–1.97) | 1.12 (0.80–1.58) | ref | 0.009 |
| Model 4 | 2.83 (1.46–5.47) ** | 1.30 (0.80–2.10) | 1.11 (0.77–1.60) | ref | 0.01 |
Model1; unadjusted, Model2; adjusted for age, gender, Model3; Model2+ diabetes mellitus, coronary artery disease, heart failure, stroke, Model4; Model3+ systolic blood pressure, total cholesterol, eGFR, serum albumin, hemoglobin, white blood cell, diuretics, angiotensin-converting-enzyme inhibitor/angiotensin receptor blockers
* P < 0.05
** P < 0.01