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A) The predicted BH3 regions of Hrk (i.e., Hrk_1, residues 28–50 and Hrk_2, residues 63–85) are aligned to the Puma BH3 as a reference. B-C) The 3D models of the complexes between Bcl2a1 and Hrk_1 or Hrk_2 are shown with the residues important for the intermolecular interactions, in comparison with the experimentally-derived complex.
