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. 2019 Nov 17;18(24):3432–3441. doi: 10.1080/15384101.2019.1673619

Figure 4.

Figure 4.

Catalpol inhibited the transcriptional activity of NF-κB by decreasing the intracellular ROS levels. The protein levels of IκBα and nucleus p65 (a), the nuclear translocation of p65 (b) detected by immunofluorescence assays in mouse cardiomyocytes in NG, HG and HG+Catalpol (4 mg/ml) groups. **P < 0.01 vs. NG group; ##P < 0.01 vs. HG group. n = 3. The protein levels of IκBα and nucleus p65 (c), the nuclear translocation of p65 (d) in mouse cardiomyocytes treated with HG and/or Catalpol for 24 h or together with NAC (10 mM) or XO/HX (50 mM) for 72 h. **P < 0.01 vs. HG group; ##P < 0.01 vs. HG+Catalpol group. n = 3.