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. 2019 Nov 18;18(24):3562–3580. doi: 10.1080/15384101.2019.1691796

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 5. — Two other members (FGF16/20) of the FGF9 subfamily also inhibit the differentiation of C2C12 cells. Fluorescence images of C2C12 cells at differentiation day 3 after FGF16 (a) and FGF20 (b) treatment. Summary data for FI for control and FGF16 (c) and FGF20 (d) treatment groups. Compared to control, the FI for FGF16 and FGF20 (10 ng/mL and 50 ng/mL) did not change significantly, while FI for FGF16 and FGF20 (100ng/mL) decreased significantly (n = 3; compared to control, p < 0.05). Calibration bar = 100 µm.