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. 2019 Nov 21;19(1):109–123. doi: 10.1080/15384101.2019.1693748

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Figure 1. — p53RR does not rescue embryonic lethality caused by deletion of Mdm2. (a) Observed and expected genotype distribution of newborn offspring from matings of Mdm2^+/Δ7−9;Trp53^+/RR mice (total number of pups n = 144; contingency test P = 0.032). (b) Observed and expected genotype distribution of newborn offspring from matings Mdm2^+/Δ7−9; Trp53+/− mice (total number of pups n = 137; contingency test P = 0.3044). (c) Observed and expected genotype distribution of newborn offspring from matings Mdm2^+/Δ7−9; Trp53^RR/RR mice (total number of pups n = 187; contingency test P < 0.0001).