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. 2019 Nov 22;19(1):67–83. doi: 10.1080/15384101.2019.1693118

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This work was authored as part of the Contributor’s official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.

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Figure 5. — Gene Set Enrichment Analysis Pathways that met a FDR q-value cutoff of q ≤ 0.1 in WT cells: comparison of WT response to the remaining 6 genotypes. The GSEA Pathway FDR q-values generated for each genotype were compared for the 24 up-regulated pathways that were significant in WT cells based on a q-value of ≤ 0.1. The q-values of each genotype, each based on their own probe set list, were clustered to determine the similarities and differences between the 7 genotypes based on the WT response to IR.