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Recombinant TGF-β induces the expression of xenobiotic nuclear receptor PXR. (a and b) qRT-PCR (a) and immunoblot analysis (b) of PXR and CAR in control, TGF-β and TGF-β+ LY2157299 treated HepG2 cells. Asterisks represent significant differences (p< 0.05 (*), **p < 0.005, ***p < 0.0005). Data are mean ± SD or representative of three independent experiments performed in triplicate.
