TABLE II.

Correlation between each Edmonton Symptom Assessment System (ESAS) symptom and the EQ-5D-3L^a health utility score (HUS)

ESAS symptom	Responses (n)	Spearman correlation with HUS	p Value	Univariable regression analysis		p Value	Multivariable regression analysis		p Value
				Value	95% CI		Value	95% CI
Pain	744	−0.416	<0.0001	−0.03	−0.03 to −0.02	<0.001	−0.02	−0.03 to −0.01	<0.001
Tiredness	747	−0.387	<0.0001	−0.02	−0.03 to −0.02	<0.001	−0.01	−0.02 to −0.001	0.03
Nausea	746	−0.231	<0.0001	−0.03	−0.03 to −0.02	<0.001	0.0002	−0.01 to 0.01	0.97
Depression	743	−0.354	<0.0001	−0.03	−0.03 to −0.02	<0.001	−0.02	−0.02 to −0.01	<0.001
Anxiety	741	−0.311	<0.0001	−0.02	−0.03 to −0.02	<0.001	−0.002	−0.01 to 0.01	0.64
Drowsiness	746	−0.306	<0.0001	−0.02	−0.02 to −0.02	<0.001	0.002	−0.005 to 0.01	0.53
Appetite	745	−0.277	<0.0001	−0.02	−0.03 to −0.02	<0.001	−0.002	−0.01 to 0.004	0.50
Well-being	738	−0.345	<0.0001	−0.02	−0.02 to −0.01	<0.001	0.003	−0.003 to 0.01	0.30
Shortness of breath	746	−0.204	<0.0001	−0.02	−0.02 to −0.01	<0.001	0.002	−0.005 to 0.01	0.62

^aEuroQol Research Foundation, Rotterdam, Netherlands.

CI = confidence interval.