TABLE III.

Regression analysis^a of clinico-demographic characteristics of the original cohort

Characteristic	Univariable analysis		p Valueb	Global p valueb	Multivariable analysis		Global p valueb
	Estimate	95% CI			Estimate	95% CI
Age	0.0001	−0.0006 to 0.0009					0.69
Sex				<0.001			<0.001
Women	Reference				Reference
Men	0.04	0.02 to 0.07			0.05	0.02 to 0.07
Education				0.01			0.008
No university or college	Reference				Reference
University or college	0.03	0.01 to 0.05			0.03	0.01 to 0.05
Household income				0.04
≤$100,000	Reference
>$100,000	0.03	0.001 to 0.06
Marital status				0.02
Married or living with partner	Reference
Other	−0.03	−0.05 to −0.004
Ethnicity				0.08
White	Reference
Other	−0.02	−0.05 to 0.002
Disease site				0.04
Breast	Reference
Gastrointestinal	0.02	−0.02 to 0.05	0.41
Genitourinary	0.06	0.02 to 0.10	0.005
Gynecologic	−0.02	−0.06 to 0.03	0.43
Hematologic malignancies	0.01	−0.03 to 0.05	0.56
Thoracic and head-and-neck	0.01	−0.03 to 0.04	0.63
Other	0.03	−0.02 to 0.08	0.26
Curative status
Curative	Reference
Palliative	0.04	−0.01 to 0.06		0.08

^aIn the univariable analysis, linear regression modelling was used to individually compare each variable with the health utility score (HUS). After stepwise selection procedures (entry: 0.10; exit: 0.05), the multivariable model identified only sex and education as being independently associated with the HUS. This multivariable model serves as the baseline model for the analysis of the relationship between the various Edmonton Symptom Assessment System symptom factors and the HUS.

^bSignificant values appear in boldface type.

CI = confidence interval.