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. 2019 Dec 23;9:19655. doi: 10.1038/s41598-019-56295-0

Table 1.

mSNP imbalance in the TRPM8 gDNA region and TRPM8 cDNA in DRG samples heterozygous for reduced migraine risk SNPs rs10166942 and rs17862920.

DRG sample ID SNP ID Average reads (gDNA) Average allelic imbalance (gDNA)a Average reads (cDNA) Average allelic expression imbalance (cDNA)a Absolute fold change in allelic expressionb
379630 rs11562975 19,899 0.98 22,034 0.57 1.7
385164 rs11562975 16,624 1.14 30,039 0.41 2.4
390387 rs11562975 21,689 1.06 19,849 0.63 1.6
390388 rs28901637 735,899 0.95 632,781 0.41 2.4
397628 rs13004520 460,612 1.02 148,654 0.01 99.0
397629 rs11562975 409,588 0.94 367,027 0.12 8.2

aNumber of reads for minor allele divided by number of reads for common allele at the gDNA or transcript levels. bFold change in allelic expression regardless of which allele is increased in expression. cDNA, complementary DNA; DRG, dorsal root ganglia; gDNA, genomic DNA; SNP, single-nucleotide polymorphism.