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. 2019 Dec 17;13:539. doi: 10.3389/fncel.2019.00539

FIGURE 2.

FIGURE 2

Pcp2-Cre;Rack1F/F mutant mice show impaired motor coordination and hyperactivity. (A) Balanced beam experiment shows impaired motor balance in Pcp2-Cre;Rack1F/F mutant mice. Mean ± SEM, ∗∗p < 0.0001, n = 10. (B) Time spent on the accelerating rotarod for Rack1F/F control and Pcp2-Cre;Rack1F/F mutant mice. Mean ± SEM, ∗∗p < 0.0001, n = 11. (C) Traces of locomotor activity in Rack1F/F control and Pcp2-Cre;Rack1F/F mutant mouse in an open field test (OFT). (D) Averaged group data of total distance traveled in control and mutant mice in the OFT. Mean ± SEM, ∗∗p = 0.0062, n = 8. (E) Averaged group data of center distance traveled in control and mutant mice in the OFT. Mean ± SEM, ∗∗p = 0.0096, n = 8. (F) Averaged group data of the time spent in the central zone in control and mutant mice. Mean ± SEM, ∗∗p = 0.0624, n = 8, n.s. = not significant.