Table 3.
Multivariable Regression Models of Cortical Surface Area and Sulcal Depth.
| Clinical Risk Factors | Multivariable regression | P value |
|---|---|---|
| Coefficients (95% CI) | ||
| Surface Area | ||
| Male Sex | 6626.74 (3444.97, 9808.51) | <0.001 |
| Intrauterine growth restriction | −8773.05 (−14955.95, −2590.14) | 0.006 |
| Head circumference at birth | 453.60 (−246.23, 1153.43) | 0.201 |
| Maternal breast milk duration (days) | 327.29 (86.98, 567.61) | 0.008 |
| Postmenstrual age | 3621.56 (1023.68, 6219.43) | 0.007 |
| Injury score on structural MRI | 133.81 (−697.31, 964.94) | 0.750 |
| Bronchopulmonary dysplasia | −5508.80 (−9603.97, −1413.64) | 0.009 |
| Sulcal Depth | ||
| Gestational age | 0.36 (0.09, 0.62) | 0.009 |
| Z-score of birth weight | 0.49 (−0.19, 1.17) | 0.154 |
| Postmenstrual age | 0.37 (−0.44, 1.18) | 0.364 |
| Injury score on structural MRI | 0.13 (−0.14, 0.40) | 0.348 |
| Retinopathy of prematurity | −1.44 (−2.76, −0.13) | 0.032 |