Table 4.

Multivariate regression associating BPD with surface area for each individual lobe, after controlling for important covariates.

	Coefficients (95% CI)	P value
Occipital Lobe Surface Area
Male Sex	384.60 (56.20, 713.00)	0.022
Intrauterine growth restriction	−916.76 (−1554.92, −278.60)	0.005
Head circumference at birth	10.12 (−62.11, 82.35)	0.781
Maternal breast milk duration (days)	29.09743 (4.29, 53.90)	0.022
Postmenstrual age	118.36 (−149.78, 386.49)	0.383
Injury score on structural MRI	5.72 (−80.06, 91.51)	0.895
Bronchopulmonary dysplasia	−548.98 (−971.65, −126.30)	0.012
Parietal Lobe Surface Area
Male Sex	658.36 (285.90, 1030.82)	0.001
Intrauterine growth restriction	−952.96 (−1676.74, −229.19)	0.010
Head circumference at birth	80.90 (−1.03, 162.82)	0.053
Maternal breast milk duration (days)	38.83 (10.69, 66.96)	0.007
Postmenstrual age	505.56 (201.45, 809.67)	0.001
Injury score on structural MRI	−11.61 (−108.90, 85.68)	0.813
Bronchopulmonary dysplasia	−532.13 (−1011.52, −52.75)	0.030
Temporal Lobe Surface Area
Male Sex	660.71 (320.71, 1000.71)	<0.001
Intrauterine growth restriction	−791.03 (−1451.72, −130.34)	0.020
Head circumference at birth	36.14 (−38.64, 110.92)	0.339
Maternal breast milk duration (days)	35.21 (9.53, 60.89)	0.008
Postmenstrual age	403.11 (125.51, 680.71)	0.005
Injury score on structural MRI	58.78 (−30.03, 147.59)	0.192
Bronchopulmonary dysplasia	−573.45 (−1011.05, −135.86)	0.011
Frontal Lobe Surface Area
Male Sex	1307.21 (740.90, 1873.52)	<0.001
Intrauterine growth restriction	−1399.86 (−2500.33, −299.39)	0.013
Head circumference at birth	86.16 (−38.40, 210.72)	0.173
Maternal breast milk duration (days)	50.82 (8.04, 93.59)	0.020
Postmenstrual age	635.40 (173.01, 1097.78)	0.008
Injury score on structural MRI	17.56 (−130.37, 165.49)	0.814
Bronchopulmonary dysplasia	−906.57 (−1635.45, −177.69)	0.015