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. 2019 Dec 17;10:1273. doi: 10.3389/fgene.2019.01273

Figure 4.

Figure 4

(A) EV EpCAM expression in serum samples from PDAC patients and healthy donors .**, P-value = 0.0011. (B) ROC curve of the ability to distinguish PDAC and healthy controls based on EV EpCAM signal. (C) Kaplan-Meier curve of overall survival time of patients with above average (high expression) and below average (low expression) serum EV EpCAM signal. (DF) Difference in EV EpCAM signal in healthy controls and PDAC patients stratified by their histologic grade, tumor stage, and lymph node involvement (Data were analyzed as described in the Materials and Methods section and represent mean ± SEM; n = 6 replicates/sample). (D) **, P-value = 0.0053; ns, P-value = 0.9998. (E) **, P-value = 0.0018; ns, P-value = 0.3182. (F) *, P-value = 0.0299; ns, P-value = 0.9808.