Table 2.
Relationships between epidemiologic parameters and telomere length of cfDNA from baseline and follow-up time-points.
| Variables | Unadjusted modela | Adjusted modelb | ||
|---|---|---|---|---|
| Regression coefficient (95%CI) | P | Regression coefficient (95%CI) | P | |
| Age | −0.009 (−0.012, −0.006) | <0.001 | −0.009 (−0.012, −0.005) | <0.001 |
| Sex | ||||
| (Female = 0, Male = 1) | −0.056 (−0.132, 0.020) | 0.150 | −0.050 (−0.169, 0.069) | 0.409 |
| Smoking | ||||
| (Never = 0, Ever = 1) | −0.079 (−0.147, −0.011) | 0.024 | −0.040 (−0.147, 0.066) | 0.455 |
| Drinking | ||||
| (Never = 0, Ever = 1) | −0.008 (−0.076, 0.061) | 0.824 | 0.042 (−0.049, 0.133) | 0.366 |
| H. pylori infection | ||||
| (Negative = 0, Positive = 1) | −0.025 (−0.096, 0.046) | 0.490 | −0.044 (−0.114, 0.027) | 0.223 |
a
Univariate linear mixed model.
b
Multivariate linear mixed model adjusting for age, sex, smoking, alcohol intake, and H. pylori infection status.
CI, confidence interval; H. pylori, Helicobacter pylori.