Table 3. Comparison of MSI status, LN metastasis, and LVI depth.
| Variables | pT1a (n=585) | pT1b (n=571) | |||||
|---|---|---|---|---|---|---|---|
| MSS (n=554) | MSI-H (n=31) | P-value | MSS (n=517) | MSI-H (n=54) | P-value | ||
| LN metastasis | 0.755 | 0.298 | |||||
| Yes | 13 (2.35) | 1 (3.23) | 13/90 (16.0/20.6)* | 0/14 (0.0/29.2)* | 0.175† | ||
| No | 541 (97.65) | 30 (96.77) | 68/346 (84.0/79.4)* | 6/34 (100.0/70.8)* | 0.287‡ | ||
| LVI | 0.755 | 0.027 | |||||
| Yes | 13 (2.35) | 1 (3.23) | 11/118 (13.6/27.1)* | 3/18 (50.0/37.5)* | 0.129† | ||
| No | 541 (97.65) | 30 (96.77) | 70/318 (86.4/72.9)* | 3/30 (50.0/62.5)* | 0.019‡ | ||
MSI = microsatellite instability; LN = lymph node; LVI = lymphovascular invasion; MSS = microsatellite stable; MSI-H = microsatellite instability-high.
*Sm1 (<500 μm)/Sm2, 3 (≥500 μm); number (%); †P-value of χ2 or Fisher's exact test between MSI status and LN metastasis/LVI on Sm1 stage gastric cancer; ‡P-value of χ2 or Fisher's exact test between MSI status and LN metastasis/LVI on Sm2, 3 stage gastric cancer.