Table 4. Multivariate analysis of the matched population for OS and CSS.
Characteristics | OS | CSS | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | ||
Age (yr) | |||||||
<45 | Ref. | Ref. | |||||
45–74 | 1.141 | 0.851–1.530 | 0.378 | 0.976 | 0.710–1.342 | 0.882 | |
>75 | 1.869 | 1.321–2.645 | 0 | 1.344 | 0.898–2.012 | 0.150 | |
Sex | |||||||
Female | Ref. | Ref. | |||||
Male | 1.128 | 0.919–1.386 | 0.250 | 0.974 | 0.765–1.239 | 0.829 | |
Marital status | |||||||
Married | Ref. | Ref. | |||||
Single | 1.042 | 0.834–1.302 | 0.717 | 0.989 | 0.760–1.286 | 0.933 | |
Race | |||||||
White | Ref. | Ref. | |||||
Black | 1.266 | 0.925–1.732 | 0.141 | 1.262 | 0.871–1.830 | 0.218 | |
Other* | 0.725 | 0.557–0.944 | 0.017 | 0.699 | 0.512–0.955 | 0.025 | |
Registry | |||||||
Central | Ref. | Ref. | |||||
East | 0.776 | 0.551–1.094 | 0.148 | 0.699 | 0.471–1.037 | 0.075 | |
West | 0.974 | 0.702–1.352 | 0.877 | 0.916 | 0.630–1.333 | 0.646 | |
Location | |||||||
Proximal third | Ref. | Ref. | |||||
Mid third | 0.728 | 0.493–1.075 | 0.111 | 0.695 | 0.447–1.081 | 0.106 | |
Distal third | 0.801 | 0.613–1.046 | 0.103 | 0.640 | 0.468–0.876 | 0.005 | |
Lesser curvature | 0.807 | 0.577–1.128 | 0.209 | 0.672 | 0.452–1.001 | 0.050 | |
Greater curvature | 1.065 | 0.725–1.565 | 0.748 | 0.825 | 0.519–1.311 | 0.415 | |
Overlapping lesion | 0.896 | 0.645–1.247 | 0.516 | 0.920 | 0.639–1.325 | 0.654 | |
Size | |||||||
≤5 cm | Ref. | Ref. | |||||
>5 cm | 1.202 | 0.990–1.460 | 0.063 | 1.372 | 1.092–1.724 | 0.007 | |
NLNE | |||||||
<15 | Ref. | Ref. | |||||
≥15 | 0.711 | 0.587–0.861 | 0 | 0.778 | 0.621–0.975 | 0.029 | |
Stage | |||||||
II | Ref. | Ref. | |||||
III | 1.866 | 1.522–2.287 | 0 | 1.889 | 1.484–2.405 | 0 | |
Chemotherapy | |||||||
Chemotherapy− | Ref. | Ref. | |||||
Chemotherapy+ | 0.935 | 0.674–1.296 | 0.686 | 1.127 | 0.742–1.711 | 0.576 | |
Radiation | |||||||
Radiation− | Ref. | Ref. | |||||
Radiation+ | 0.778 | 0.644–0.940 | 0.009 | 0.757 | 0.607–0.944 | 0.014 |
OS = overall survival; CSS = cancer-specific survival; HR = hazard ratio; CI = confidence interval; NLNE = number of lymph nodes examined.
*American Indian/AK Native, Asian/Pacific Islander.