Fig. 5.
Mechanotransduction functional studies. a Boxplots presenting number of detected genes per morphotypes in β1-integrin-inhibited treatment (left panel), Src-inhibited treatment (middle panel), and Src-overexpressed treatment (right panel). b PCA plots based on all expressed genes for β1-integrin-inhibited treatment (top panel), Src-inhibited treatment (middle panel), and Src-overexpressed treatment (bottom panel). c The activation z-scores of the enriched IPA canonical pathways for different pairwise morphotypic comparisons are represented by heatmaps. Blue = inhibited and red = activated. Src-inhibited treatment is not presented, since no pathway is significantly enriched in Src-inhibited morphotypic comparisons