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. 2019 Dec 23;9:19686. doi: 10.1038/s41598-019-56215-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Representative distal DTI/DKI parameter maps from recovered (top panel) and non-recovered (bottom panel) cut/repair nerves 12 weeks after injury. Shown are maps of DTI (FA, AD, RD, and MD) and DKI (AK, RK, and MK) parameters along the non-diffusion weighted image (b = 0 s/mm²) from a single distal slice. Note the reduced FA (blue hues) and elevated diffusivities (yellow hues) in the non-recovered nerve relative the recovered nerve. In addition, note the reduce kurtosis measures (blue hues) in the non-recovered nerve.