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. 2019 Dec 23;9:19686. doi: 10.1038/s41598-019-56215-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Longitudinal behavioral data after sham (black lines), crush (red lines) and cut/repair injuries (blue lines). Results are shown for both FF (left panel) and SFI (right panel). The longitudinal time course (from injury to euthanasia) for each individual animal is plotted with thin lines, while the mean time course within each cohort is plotted with thick lines. Note the sharp decay in FF and SFI for both cohorts immediately after surgery, with the largest contrast between injury types at 4 weeks (vertical black dashed line). These results indicate a faster behavioral recovery following crush relative to cut/repair injuries, with crush injuries nearly recovered by four weeks.