Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 17;9:1390. doi: 10.3389/fonc.2019.01390

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Matrone, Torregrossa, Sensi, Cappellani, Baronti, Ciampi, Molinaro, Ugolini, Aghababyan, De Napoli, Latrofa, Materazzi, Basolo, Vitti and Elisei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) CT scan section of thyroid neoplasia. (B) CT scan section of lung neoplasia. (C) Undifferentiated carcinoma with marked nuclear atypia intermixed to thyroid follicles in thyroid Tru-cut. Magnifications: x200. (D) Adenocarcinoma with mucinous differentiation in bronchial biopsy. Magnifications: x200. (E–G) Immunohistochemistry in thyroid Tru-cut showing focal immunoreactivity for TTF-1 and absence of immunoreactivity for Thyroglobulin and PAX-8 markers. Original magnifications: x200. (H–J) Immunohistochemistry in bronchial biopsy showing absence of immunoreactivity for TTF-1, Thyroglobulin, and PAX-8 markers. Original magnifications: x200. (K,L) Mass spectrometry of thyroid neoplasia with substitution c.34G>T (p.G12C) in the codon 12 of kRAS gene. (M,N) Mass spectrometry of lung neoplasia with substitution c.34G>T (p.G12C) in the codon 12 of kRAS gene.