Figure 1. The BP device: design components and function.
(a) Annotated schematic illustrating the fundamental components and functions of the BP device. (b) Digital images of the empty device for mouse implantation from the top view (left), side view (center), and bottom view (right). (c) Annotated schematic illustrating device components and dimensions; schematic and digital image of the cell encapsulation module (left panel); schematic of each component, including the (top to bottom) titanium frame cap, cell encapsulation module, alginate-impregnated nylon mesh, and titanium frame base (center panel); schematic of the cell encapsulation module, featuring the PDMS sealing O-ring (right panel). (d) SEM image of the PTFE nanomembrane. (e) A digital image of a water droplet on the PTFE nanomembrane. (f) A contact angle goniometer-captured image of a water droplet sliding on the PFC-infused PTFE nanomembrane after tilting to ~5°. (g) SEM images of the PVDF-HFP scaffold displaying its spiral configuration and porous structure. (h) Chemical structure of the PVDF-HFP copolymer. (i) SEM image of the nylon mesh. (j) Confocal image of the alginate-impregnated nylon mesh.
