Table 2.
Clinical features of infection for the overall cohort and by causative organism
| Overall Cohort (n=103) | CONS (n=57) | S. aureus (n=19) | Gram-negative organisms (n=9) | |
|---|---|---|---|---|
| Fever, n (%) | 83 (81) | 44 (77) | 16 (84) | 8 (89) |
| Lethargy, n (%) | 28 (27) | 10 (18) | 7 (37) | 3 (33) |
| Headache, n (%) | 10 (10) | 3 (5) | 3 (16) | 1 (11) |
| Nausea or vomiting, n (%) | 57 (55) | 30 (53) | 7 (37) | 6 (67) |
| Abdominal pain, n (%) | 31 (30) | 15 (26) | 7 (37) | 3 (33) |
| Surgical site changes, n (%) * | 60 (58) | 27 (47) | 15 (79) | 6 (67) |
| CSF leak | 24 (23) | 14 (25) | 7 (37) | 3 (33) |
| Neurologic changes, n (%) | 25 (24) | 14 (25) | 6 (32) | 2 (22) |
| Leukocytosis, n (%) * | 49 (48) | 29 (51) | 12 (63) | 1 (11) |
| Leukopenia, n (%) * | 6 (6) | 1 (2) | 2 (11) | 2 (22) |
| Positive CSF gram stain, n (%) | 51 (62) | 32 (67) | 6 (50) | 6 (67) |
| CSF pleocytosis, n (%) | 98 (95) | 56 (98) | 17 (89) | 9 (100) |
| Imaging changes, n (%) | 20 (27) | 13 (30) | 1 (11) | 3 (43) |
| Intermittent negative culture, n (%) | 13 (13) | 6 (11) | 4 (21) | 1 (11) |
*
p<0.05.
CONS coagulase-negative Staphylococcus, CSF cerebrospinal fluid