Table 3.
Association between individual reproductive and menstrual factors and SS
| SS n=1320 |
Sicca Control n=1360 |
|||||
|---|---|---|---|---|---|---|
| n(%) | n(%) | P | OR | 95% CI | ||
| Menarche age (mean, SD) | 13.1(1.7) | 12.8(1.7) | <0.00001 | |||
| Menarche ≤ 10 yrs (n) | 53 | 70 | 0.06 | |||
| Pregnancies* | 0 | 229(17) | 217(16) | 0.29 | ref | |
| 1 | 159(12) | 161(12) | 0.8 | 0.60–1.15 | ||
| 2 | 319(24) | 332(24) | 0.9 | 0.65–1.14 | ||
| 3 | 289(22) | 295(22) | 0.8 | 0.62–1.11 | ||
| >3 | 322(24) | 352(26) | 0.8 | 0.63–1.12 | ||
| Hormone Use* | No | 1135(86) | 1074(79) | <0.001 | ref | 0.68–1.08 |
| Yes | 185(14) | 285(21) | 0.86 | |||
| Hysterectomy* | No | 1117(85) | 1037(76) | <0.001 | ref | |
| Yes | 203(15) | 322(24) | 0.7 | 0.57–0.89 | ||
| Menopause (mean, SD) | 47.4(5.8) | 47.2 | 0.55 | |||
| Menopause ≥ 53 | 105 | 134 | 0.39 | |||
*
Data missing for pregnancies (n=5), hormone use (n=1), and hysterectomy (n=1) categories