Figure 4. Overexpression of IL17R counteracted the effect of IL-6 AB on CAA-treated HepG2 cells.
(A) Glucose consumption in HepG2. (B) Representative band of IL-17R, p-IR, and GLUT1 in IR group, IR+CAA group, IR+CAA+IL-6 AB group, and IR+CAA+IL-6 AB+IL17R group detected by Western blotting. (C,D) Th17/Treg ratio cells was investigated by flow cytometry assay. (E) IL-17 concentration in the IR group, IR+CAA group, IR+CAA+IL-6 AB group, and IR+CAA+IL-6 AB+IL17R group detected by ELISA. *P<0·05 versus IR+CAA+IL-6 AB group. Data are represented as the mean ± SD.
