Figure 2.

Changes of total brain ketone bodies during nutrition. Brain interstitial tissue concentrations of total ketone bodies (KB, including acetoacetate [AcAc] and (β-hydroxybutyrate [BHB]) were measured with cerebral microdialysis (CMD) in patients with TBI (n = 34) at baseline fasting vs. intermediate nutrition ((7.5 Kcal/kg) and stable nutrition (15 Kcal/kg)). Box-plots illustrate median (midline), 25–75th percentiles (lower and upper part of the boxes), 10–90th percentiles (lower and upper part of the whiskers). **p = 0.001; *p = 0.01 for comparison of fasting state vs. nutrition states.