Table 2.
SMRs over 5 years of follow-up of patients newly diagnosed with tuberculosis compared with the São Paulo state population, matched by age, sex, and calendar year
|
Among all patients who started treatment |
Among those alive after 1 year |
||||||
|---|---|---|---|---|---|---|---|
| Whole population (n=15 342) | Population without any of the six exposures* (n=10 182) | Population with at least one of the six exposures* (n=5160) | Whole population (n=14 011) | Population without any of the six exposures* (n=9347) | Population with at least one of the six exposures* (n=4664) | ||
| Overall | 6·47 (6·22–6·73) | 5·72 (5·43–6·02) | 8·06 (7·56–8·58) | 3·93 (3·71–4·17) | 3·31 (3·06–3·57) | 5·25 (4·80–5·73) | |
| Stratified by age, years* | |||||||
| 15–25 | 7·63 (6·28–9·19) | 5·28 (4·07–6·75) | 7·56 (5·56–10·06) | 5·29 (4·07–6·75) | 4·77 (3·37–6·55) | 6·29 (4·11–9·22) | |
| >25–35 | 11·73 (10·47–13·09) | 8·90 (7·62–10·33) | 10·6 (8·95–12·47) | 7·31 (6·22–8·52) | 6·33 (5·04–7·86) | 8·67 (6·88–10·79) | |
| >35–45 | 13·54 (12·44–14·72) | 10·76 (9·58–12·05) | 13·69 (12·04–15·50) | 8·30 (7·34–9·35) | 6·95 (5·84–8·21) | 10·39 (8·70–12·32) | |
| >45–55 | 8·15 (7·49–8·84) | 6·79 (6·07–7·58) | 8·46 (7·44–9·58) | 4·71 (4·15–5·31) | 4·01 (3·36–4·74) | 5·83 (4·85–6·96) | |
| >55–65 | 5·38 (4·88–5·92) | 4·68 (4·12–5·28) | 5·39 (4·58–6·30) | 3·16 (2·73–3·63) | 2·91 (2·41–3·49) | 3·63 (2·86–4·55) | |
| >65 | 3·27 (2·99–3·58) | 2·71 (2·43–3·00) | 3·09 (2·59–3·67) | 1·92 (1·68–2·20) | 1·79 (1·52–2·10) | 2·33 (1·80–2·98) | |
| Stratified by sex | |||||||
| Female | 7·33 (6·76–7·94) | 6·59 (5·99–7·24) | 10·31 (8·81–11·99) | 4·25 (3·76–4·78) | 3·67 (3·16–4·23) | 6·62 (5·27–8·20) | |
| Male | 6·23 (5·95–6·52) | 5·42 (5·10–5·76) | 7·71 (7·19–8·26) | 3·85 (3·60–4·11) | 3·19 (2·91–3·48) | 5·05 (4·58–5·55) | |
| Stratified by follow-up, year | |||||||
| 1st | 16·54 (15·66–17·45) | 15·33 (14·31–16·41) | 19·07 (17·43–20·83) | .. | .. | .. | |
| 2nd | 4·45 (3·99–4·94) | 3·91 (3·40–4·49) | 5·56 (4·68–6·57) | .. | .. | .. | |
| 3rd | 3·82 (3·39–4·28) | 3·35 (2·87–3·88) | 4·80 (3·98–5·75) | .. | .. | .. | |
| 4th | 3·32 (2·93–3·76) | 2·56 (2·14–3·03) | 4·95 (4·10–5·91) | .. | .. | .. | |
| 5th | 3·47 (3·04–3·93) | 2·76 (2·31–3·28) | 5·00 (4·11–6·04) | .. | .. | .. | |
| Stratified by previous treatment outcome | |||||||
| Treatment success | .. | .. | .. | 3·47 (3·25–3·70) | 2·91 (2·67–3·17) | 4·71 (4·26–5·20) | |
| Treatment failure | .. | .. | .. | 5·23 (3·60–7·34) | 5·81 (3·45–9·19) | 4·66 (2·61–7·69) | |
| Loss to follow-up or not evaluated | .. | .. | .. | 8·75 (7·59–10·03) | 7·89 (6·47–9·53) | 9·91 (8·06–12·07) | |
Data are SMRs (95% CI). SMR=standardised mortality ratio.
*
The six exposures are incarceration, homelessness, alcohol and drug use, diabetes, and mental disorders.