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. 2019 Sep-Oct;13(5):281–287. doi: 10.1016/j.jcct.2019.03.007

Table 2.

Randomized controlled trials of CCTA improving outcomes in acute chest pain35,36,66,67.

ACRIN-PA BEACON CATCH CT-COMPARE CT-STAT Nabi et al. PERFECT PROSPECT ROMICAT-II
Number of patients 1368 490 576 562 699 598 395 400 1000
CCTA vs Stress ECG, stress imaging Stress ECG, MPI Stress ECG, MPI Stress ECG MPI MPI Stress echo., MPI MPI Stress ECG, Stress echo., MPI
Age (mean years) 50 54 56 52 50 53 60 57 54
Female (%) 54 47 45 42 54 56 54 63 47
Follow-up (months) 12 1 19 12 6 7 12 12 1

ACRIN-PA, CT Angiography for Safe Discharge of Patients with Possible Acute Coronary Syndromes; BEACON, Better Evaluation of Acute Chest Pain with Coronary Computed Tomography Angiography; CATCH, CArdiac cT in the treatment of acute CHest pain; CT-COMPARE, CT Coronary Angiography Compared to Exercise ECG; CT-STAT, Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment; PERFECT, Prospective First Evaluation in Chest Pain; PROSPECT, Prospective Randomized Outcome trial comparing radionuclide Stress myocardial Perfusion imaging and ECG-gated coronary CT angiography; ROMICAT-II, Rule Out MI/ischaemia Using Computer Assisted Tomography; ECG, electrocardiogram; MPI, myocardial perfusion imaging; echo., echocardiography.