Table 1.
Pathways identified for differentially expressed mRNAs and lncRNAs.
| Pathway | Genes | lncRNA |
|---|---|---|
| Pancreatic secretion, Insulin secretion, Regulation of lipolysis in adipocytes | ADCY8 | AC034229.2,AP001372.2,ITGB2.AS1 |
| cAMP signaling pathway | ADCY8 | AC034229.2,AP001372.2,ITGB2.AS1 |
| DRD5 | ||
| Chemokine signaling pathway | ADCY8 | AC034229.2,AP001372.2,ITGB2.AS1 |
| GSK3A | AC089998.1,AL031123.1,LINC01783 | |
| Calcium signaling pathway | ADCY8 | AC034229.2,AP001372.2,ITGB2.AS1 |
| PHKG2 | AC239798.2,AL118505.1 | |
| DRD5 | ||
| Lysosome | AP3B1 | AC110079.2,AL121603.2 |
| Biosynthesis of amino acids | CBS | AC024614.4,AC239798.2,AL591623.1 |
| Hippo signaling pathway | FRMD6 | AC089998.1,AC105275.2,LINC01783 |
| DLG3 | AC010327.4,AL391987.3,CSNK1G2.AS1,LINC00967,LINC01258 | |
| BMP5 | AC110079.2,AL121603.2 | |
| Glycine, serine, and threonine metabolism | GRHPR | AC092620.3,AL031123.1 |
| CBS | AC024614.4,AC239798.2,AL591623.1 | |
| Hematopoietic cell lineage, Jak-STAT signaling pathway | IL11 | AC004949.1,AP001043.1 |
| TGF-beta signaling pathway | INHBE | AC004949.1,AC034229.2,AC105275.2,AP001372.2 |
| BMP5 | AC110079.2,AL121603.2 | |
| Cytokine–cytokine receptor interaction | INHBE | AC004949.1,AC034229.2,AC105275.2,AP001372.2 |
| TNFRSF13C | AC110079.2,AL121603.2 | |
| IL11 | AC004949.1,AP001043.1 | |
| Extracellular matrix-receptor interaction | LAMC1 | |
| Signaling pathways regulating pluripotency of stem cells | PCGF5 | AC239798.2,AL118505.1,MAP3K14.AS1,RP11.680G24.5 |
| INHBE | AC004949.1,AC034229.2,AC105275.2,AP001372.2 | |
| PCGF6 | AC034229.3,RMRP | |
| Insulin signaling pathway, Glucagon signaling pathway | PHKG2 | AC239798.2,AL118505.1 |
| B cell receptor signaling pathway | PIK3AP1 | AC004852.2,AC008669.1,AC110079.2,AL391987.3 |
| PI3K-Akt signaling pathway | PIK3AP1 | AC004852.2,AC008669.1,AC110079.2,AL391987.3 |
| LAMC1 | ||
| Mitogen-Activated Protein Kinase signaling pathway | PPP5D1 | AC110079.2,AL121603.2,AL391261.2,AP001043.1 |
| MAPK8IP1 | AC089998.1,AC105275.2,LINC01783 | |
| Proteasome | PSMD3 | AC089998.1,AC105275.2,LINC01783 |
| RNA transport | RGPD1 | CSNK1G2.AS1,ITGB2.AS1,LINC01258,RP11.475I24.8 |
| RPP30 | AC034229.3,AL391987.3,RMRP | |
| Primary immunodeficiency, NF-kappa B signaling pathway | TNFRSF13C | AC110079.2,AL121603.2 |
| Spliceosome | USP39 | AC034229.3,AC092620.3,RMRP |
Representative pathways identified from the KEGG database are indicated along with the differentially expressed mRNAs involved in each pathway. The third column of the table lists the lncRNAs correlated with the mRNAs and therefore potentially predicted to be involved in the corresponding pathways.