Table 1.
Patient characteristics.
| Patients (n = 30) |
Age/Gender | MGMT (Met ≥ 0.1) |
NK Cell Response § | SNP | PFS (months) | OS (months) |
|---|---|---|---|---|---|---|
| 1 | 55/F | U (0.07) | NO | DelC | 13.7 | 22.5 |
| 2 | 62/F | U (0.01) | NO | Wt | 12.0 | 24.4 |
| 3 | 66/M | U (0.04) | YES | DelC | 15.4 | 15.4 |
| 4 | 70/F | U (0.00) | NO | Wt | 14.7 | 17.8 |
| 5 | 49/M | U (0.00) | NO | DelC | 10.2 | 12.5 |
| 6 | 65/F | M (0.71) | YES | DelC | 20.8 | 33.9 |
| 7 | 60/M | U (0.01) | YES | DelC | 9.3 | 25.0 |
| 8 | 58/M | U (0.00) | YES | DelC | 9.4 | 22.6 |
| 9 | 50/M | U (0.00) | YES | DelC | 16.1 | 33.0 |
| 10 | 48/M | M (2.38) | YES | DelC | 4.4 | 7.8 |
| 11 | 23/F | U (0.003) | NO | Wt | 3.1 | 6.4 |
| 12 | 44/M | U (0.03) | YES | DelC | 24.2 | 38.4 |
| 14 | 62/M | M (0.46) | NO | DelC | 7.9 | 20.2 |
| 16 | 70/M | M (1.50) | YES | DelC | 17.2 | 32.8 |
| 19 | 56/M | U (0.00) | NO | Wt | 3.2 | 6.9 |
| 20 | 48/M | U (0.00) | NO | Wt | 9.0 | 12.4 |
| 21 | 53/F | M (0.47) | YES | DelC | 28.3 | 56.0 |
| 22 | 63/M | U (0.02) | YES | Wt | 6.5 | 8.1 |
| 23 | 45/M | M (0.74) | YES | DelC | >60.0 | >60.0 |
| 24 | 55/F | U (0.00) | YES | DelC | 14.0 | 28.3 |
| 25 | M/58 | M (0.18) | NO | DelC | 22.4 | 37.2 |
| 26 | F/45 | U (0.07) | NO | Wt | 12.0 | 17.6 |
| 27 | M/49 | M (0.38) | NO | Wt | 9.5 | 13.2 |
| 28 | F/54 | U (0.00) | NO | Wt | 12.0 | 15.5 |
| 29 | M/43 | M (0.56) | NO | Wt | 9.4 | 17.3 |
| 30 | M/65 | M (0.26) | NO | Wt | 18.7 | 27.0 |
| 31 | F/60 | M (1.78) | YES | Wt | 10.7 | 22.9 |
| 32 | M/62 | M (0.21) | NO | Wt | 16.1 | 33.5 |
| 33 | M/53 | U (0.04) | YES | Wt | 18.3 | 38.5 |
| 34 | M/49 | M (2.39) | YES | DelC | 12.0 | 23.3 |
Abbreviations: MGMT: O6-Methylguanine-DNA Methyltransferase, M: methylated; U: unmethylated; SNP: single nucleotide polymorphism; DelC: deletion of a cytosine; Wt: wild-type; PFS: progression free survival; OS: overall survival. § Significant activation of NK cell response evaluated as V/B ratio > 2.1.