5-HT1A	Serotonin receptor type 1A
ACF	Aberrant crypt foci
AD	Alzheimer’s disease
Aᵦ42	Amiloid beta 42
BCE	Before Common Era
BRCA-1	Breast cancer gene 1
BRCA-2	Breast cancer gene 2
cAMP	Cyclic adenosine monophosphate
CB1, CB2	Cannabinoid receptor 1,2
CBD	Cannabidiol
CBR	Cannabinoid receptor
CD-1; 4	Cluster of differentiation 1; 4
CGS	Glioma stem cells
CID 16020046	Inverse agonist at the former orphan receptor GPR55
COX	Cyclooxygenase
CT	Computed tomography scan
CXCL16	Chemokine (C-X-C motif) ligand 16
DNA	Deoxyribonucleic acid
EAE	Experimental autoimmune encephalomyelitis
EC50	Half maximal effective concentration
EGF/EGFR	Epidermal growth factor/epidermal growth factor receptor
ELISA	Enzyme-linked immunosorbent assay
EMA	European Medicine Agency
EMV	Exosome and microvesicle
ENT-1	Equilibrative nucleoside transporter-1
ET-1	Endothelin-1
FDA	Food and Drug administration
GABA	Gamma-aminobutyric acid
GI	Gastro-intestinal
GPR55	G-coupled protein receptor-55
GSC	Glioma stem cell
GW9662	Potent antagonist of Peroxisome proliferator-activated receptor gamma
GPX	Glutathione peroxidase
HUVEC	Human umbilical vein endothelial cells
HIF-1a	Regulatory subunit of the hypoxia- inducible transcription factor
i.p.	Intraperitoneal
IC50	Half maximal inhibitory concentration
ICAM	Inter-intracellular adhesion molecule
ICR	Institute of Cancer Research
IFN-γ	Interferon Gamma
IGHM	Immunoglobulin heavy constant Mu
IL-2,6,8,9,12,IL-1A; 17A/F2	Interleukin 2, 6,8,9,12, 1A, 17A/F2,
iNOS	Inducible nitric oxide synthase
Ki	Inhibitory constant binding affinity
KPC	KRAS, p53, Cre mice
MDA	Malonaldehyde
MIP-1α,1ᵦ,2	Macrophage inflammatory protein 1α,1ᵦ, 2
MMP2,9	Matrix metalloproteinase-2, 9
mRNA	Messenger RNA
Mtor	Mammalian target of rapamycin
NFκB	Nuclear factor κB
n.d.	Not determined
PAI-1	Plasminogen activator inhibitor-1
PDGF-AA	Platelet-derived growth factor subunit A
PERK	Extracellular signal-regulated kinase phosphorylation
Phospho-Akt	Phosphorylated AKT
PPARγ	Nuclear peroxisome proliferation activated receptor
PSA	Prostate-specific antigen
PTEN	Phosphatase and tensin homolog
ROS	Reactive oxygen species
RT-PRC	Real-time polymerase chain reaction
s.c.	Sub cutaneous
S100A10B	S100 calcium-binding protein A10
S1P	Sphingosine-1-phosphate
S1PR1	Sphingosine-1-phosphate receptor 1
Serpin E1	Serpin Family E Member 1
SGPL1	Sphingosine-1 phosphate lyase
SiRNA	Small interfering RNA
SOD	Superoxide dismutase
STAT-3,5	Signal transducers and activators of transcription 3,5
TGFBA	Transforming growth factor beta, alpha
THC	Tetrahydrocannabinol
THCA	Tetrahydrocannabinolic acid
TIMP1	Tissue inhibitor of matrix metalloproteinases1
TNF-α	Tumor necrosis factor α
Tp53	Tumor protein p53
TRP	Transient receptor potential
TRPA	Transient receptor potentialankyrin
TRPV1	Transient receptor potential vanilloid type1
TRPV2	Transient receptor potential vanilloid type 2
TRPM8	Transient receptor potentialmelastatin 8
uPA	Urokinase-type plasminogen activator
VEGF	Vascular endothelial growth factor
VR1, VR2	Vanilloid receptor 1, 2