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CGRP(8–37) counteracts the CGRP-induced increase in chemotherapy resistance. HNT-34 and UKK-M7 cells were pre-incubated first with or without 1 µM CGRP(8–37) for 15 min, next with or without 1 nM CGRP for 1 h, prior to addition of the indicated concentrations of araC or daunorubicin (DNR). CellTiter-Glo metabolic activity assay; means + SEM from 3 biological replicates. ns, not significant, * p < 0.05, ** p < 0.01, paired Student’s two-tailed t-test.
