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. 2019 Nov 26;20(23):5938. doi: 10.3390/ijms20235938
ACC Accumulation of compounds in cells expressed as either I/E or % of the accumulation of the reference compound azithromycin
ACC Class Class (level) of accumulation (determined from LC-MS/MS data on ACC)
AD Applicability domain
ADME Absorption distribution metabolism and excretion
AZI Azithromycin, a macrocycle antibiotic
CAD Cationic amphiphilic drug
I/E Intracellular to extracellular concentration ratio; a measure of accumulation
LC-MS/MS Liquid chromatography coupled to tandem mass spectrometry
LTR ACC Class Class (level) of accumulation (determined by an indirect method of cell imaging of lysosome volume change)
OPLS Orthogonal projections to latent structures
QSAR Quantitative structure-activity relationship model