Figure 2.

Myocardial resistivity and chemical communication through gap junction in isolated rat hearts. (A) Resistivity increases during ischemia (in grey) in both groups and rapidly recovered during reperfusion in Control hearts but not in IPoC treated ones. The inset shows the values from the last min of ischemia to the 5th min of reperfusion.* p < 0.05 by repeated measures ANOVA (B). Representative images of Lucifer yellow (LY) and rodamine (RD) spread taken from the 4th min of reperfusion indicate lower diffusion through gap junction in IPoC group. Quantitative comparison of the ratio of LY/RD for each group (n = 4 each). * p < 0.05 Control vs. IPoC by Mann-Whitney U test.