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. 2019 Nov 29;20(23):6032. doi: 10.3390/ijms20236032

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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C-peptide area under the curve (AUC) stratified by treatment group. (A) C-peptide AUC at the study’s end (52 weeks) in the intention-to-treat (ITT) population versus the 12–18-year subgroup. White bars = ITT analysis and black bars = 12–18-year subgroup. (B) C-peptide AUC during the study in the ITT population. Dotted line = placebo group, dash–dot line = AAT-60 mg/kg group, and solid line = AAT-120 mg/kg group. (C) C-peptide AUC during the study in the 12–18-year subgroup. Dotted line = placebo group, dash–dot line = AAT-60 mg/kg group, and solid line = AAT-120 mg/kg group.

C-peptide area under the curve (AUC) stratified by treatment group. (A) C-peptide AUC at the study’s end (52 weeks) in the intention-to-treat (ITT) population versus the 12–18-year subgroup. White bars = ITT analysis and black bars = 12–18-year subgroup. (B) C-peptide AUC during the study in the ITT population. Dotted line = placebo group, dash–dot line = AAT-60 mg/kg group, and solid line = AAT-120 mg/kg group. (C) C-peptide AUC during the study in the 12–18-year subgroup. Dotted line = placebo group, dash–dot line = AAT-60 mg/kg group, and solid line = AAT-120 mg/kg group.