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. 2019 Nov 24;20(23):5894. doi: 10.3390/ijms20235894
EGFR epidermal growth factor receptor
mCRC metastatic colorectal cancer
PDXs patient-derived xenografts
PI3K phosphatidylinositol-3-kinase
mTOR mammalian target of rapamycin
CRC colorectal cancer
RTK receptor tyrosine kinase
IGF1R insulin like growth factor 1 receptor
TGF-α transforming growth factor α
HB-EGF heparin-binding EGF-like growth factor
BTC betacellulin
AREG amphiregulin
EREG Epiregulin
RAS rat sarcoma
RAF rapidly accelerated fibrosarcoma
ADCC antibody-dependent cellular cytotoxicity
MAPK mitogen-activated protein kinase
KRAS KRAS proto-oncogene GTPase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PTEN phosphatase and tensin homolog
TP53 Tumor Protein P53
MEK mitogen-activated protein kinase kinase
BALB Bagg albino
BSA bovine serum albumin