| EGFR | epidermal growth factor receptor |
| mCRC | metastatic colorectal cancer |
| PDXs | patient-derived xenografts |
| PI3K | phosphatidylinositol-3-kinase |
| mTOR | mammalian target of rapamycin |
| CRC | colorectal cancer |
| RTK | receptor tyrosine kinase |
| IGF1R | insulin like growth factor 1 receptor |
| TGF-α | transforming growth factor α |
| HB-EGF | heparin-binding EGF-like growth factor |
| BTC | betacellulin |
| AREG | amphiregulin |
| EREG | Epiregulin |
| RAS | rat sarcoma |
| RAF | rapidly accelerated fibrosarcoma |
| ADCC | antibody-dependent cellular cytotoxicity |
| MAPK | mitogen-activated protein kinase |
| KRAS | KRAS proto-oncogene GTPase |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| PTEN | phosphatase and tensin homolog |
| TP53 | Tumor Protein P53 |
| MEK | mitogen-activated protein kinase kinase |
| BALB | Bagg albino |
| BSA | bovine serum albumin |