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. 2019 Nov 20;20(23):5835. doi: 10.3390/ijms20235835

Figure 4.

Figure 4

alamarBlue assay showed the cell viability as a fluorescence intensity. The HER2-overexpressing cells (SK-BR3, BT474, MDA-MB361) exposed to near-infrared photoimmunotherapy (NIR-PIT) by HER2 Affibody–IR700Dye conjugate show low fluorescence intensity. In contrast, HER2 low-expressing cells (MDA-MB231, MDA-MB468) maintained strong fluorescence intensity that was at the same level of intensity as the control cells. Data are presented as means ± standard error of the mean (s.e.m.) (n = 6; ** p < 0.01, Student’s t-test).