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Comparison of key immune regulators in Nude, NSG, and wild-type C57/Bl6 mice.
| Strain | Mature T Cells | Th1/Th2 | Mature B Cells | Immunoglobins | Macrophages | Rate of Clearance | |
|---|---|---|---|---|---|---|---|
| IgG | IgA | ||||||
| 0 | - | - | - | - | - | Defective | ↓↓ |
| Nude | - | - | Present/ Defective | - | - | + | ↓ |
| C57/Bl6 | + | Th1 Biased | + | + | + | + | ↑ |
| BALB/c | + | Th2 Biased | + | + | + | + | ↑↑ |
