Table 2.
Respiratory parameters and lung mechanics in animal experiments.
| Parameter | Group | Baseline | Lavage | Post 1 h | Post 2 h | Post 3 h |
|---|---|---|---|---|---|---|
| VE, L/min | ||||||
| Control (n = 6) | 5.2 ± 0.86 | 5.1 ± 0.86 | 5.1 ± 0.81 | 5.1 ± 0.82 | 4.9 ± 0.69 | |
| VCV (n = 6) | 5.7 ± 0.62 | 5.7 ± 0.57 | 6.0 ± 0.37 | 5.9 ± 0.34 | 5.9 ± 0.33 | |
| ASV (n = 6) | 5.5 ± 1.1 | 5.3 ± 1.0 | 5.5 ± 0.53 | 5.5 ± 0.62 | 5.5 ± 0.62 | |
| VT, mL/kg | ||||||
| Control | 10.0 ± 0.26 | 9.9 ± 0.31 | 10.0 ± 0.31 | 9.9 ± 0.35 | 10.0 ± 0.36 | |
| VCV | 10.1 ± 0.58 | 9.3 ± 0.88 | 8.0 ± 0.21&* | 8.0 ± 0.28&* | 7.9 ± 0.34&* | |
| ASV | 9.9 ± 0.42 | 9.9 ± 0.05 | 6.4 ± 0.93&*§ | 6.6 ± 1.03&*§ | 6.3 ± 1.03&*§ | |
| f, per minute | ||||||
| Control | 20.4 ± 2.8 | 20.5 ± 3.2 | 20.2 ± 3.2 | 20.2 ± 3.1 | 19.7 ± 2.3 | |
| VCV | 23.1 ± 5.6 | 25.5 ± 7.1 | 30.8 ± 6.1&* | 30.0 ± 4.9&* | 30.0 ± 4.8&* | |
| ASV | 23.9 ± 3.9 | 22.8 ± 3. 1 | 35.7 ± 3.9&* | 35.5 ± 4.5&* | 36.1 ± 4.9&* | |
| PPeak, cmH2O | ||||||
| Control | 18.9 ± 3.4 | 18.0 ± 4.5 | 17.6 ± 4.3 | 18.1 ± 4.6 | 18.5 ± 4.7 | |
| VCV | 20.1 ± 2.2 | 28.3 ± 5.2&* | 26.2 ± 3.6&* | 27.0 ± 4.4&* | 28.2 ± 5.1&* | |
| ASV | 18.5 ± 2.8 | 27.2 ± 4.3* | 19.5 ± 1.9§ | 20.0 ± 1.5§ | 21.7 ± 1.0§ | |
| Cst, mL/cmH2O | ||||||
| Control | 23.6 ± 5.3 | 26.1 ± 6.6 | 26.4 ± 6.3 | 25.6 ± 5.8 | 25.1 ± 5.7 | |
| VCV | 21.8 ± 5.4 | 13.9 ± 1.6&* | 12.1 ± 1.5&* | 11.3 ± 1.4&* | 10.8 ± 1.8&* | |
| ASV | 22.5 ± 4.9 | 15.1 ± 4.2&* | 12.7 ± 4.3&* | 12.2 ± 3.7&* | 10.7 ± 2.3&* | |
| Rrs, cmH2O/L/s | ||||||
| Control | 7.2 ± 1.2 | 7.7 ± 1.9 | 7.9 ± 1.9 | 8.1 ± 2.4 | 7.9 ± 1.9 | |
| VCV | 9.6 ± 3.3 | 9.1 ± 2.5 | 6.3 ± 2.2 | 6.7 ± 3.4 | 6.8 ± 4.3 | |
| ASV | 7.4 ± 1.4 | 10.8 ± 2.6 | 9.8 ± 2.1 | 8.9 ± 2.5 | 9.3 ± 2.9 | |
Values are expressed as the mean and SD. VE, minute ventilation; ASV, adaptive support ventilation; VCV, volume control ventilation; VT, tidal volume; f, respiratory frequency; Ppeak, peak airway pressure; Cst, static lung compliance; Rrs, resistance of the respiratory system. & p < 0.05 compared with the baseline; * p < 0.05 compared with the control group; § p < 0.05 compared with the VCV group. Differences between and within groups were tested using general linear model statistics and were adjusted for repeated measurements.