Cer |
ceramide |
SM |
sphingomyelin |
dhCer |
dihydroceramide |
S1P |
sphingosine-1-phosphate |
Sph |
sphingosine |
C1P |
ceramide-1-phosphate |
SLs |
sphingolipids |
GSLs |
glycosphingolipids |
CerS |
ceramide synthase |
DEGS |
dihydroceramide desaturase |
GalCer |
galactosylceramides |
GlcCer |
glucosylceramides |
SMase |
sphingomyelinase (): lysosomal SMase (); SMase |
ASMase |
acid sphingomyelinase |
NSMase |
neutral sphingomyelinase |
CDase |
ceramidase |
(F)FA |
(free) fatty acid |
ER |
endoplasmic reticulum |
TLC |
thin layer chromatography |
HPLC |
liquid chromatography |
HPTLC |
high performance thin layer chromatography |
LC-ESIMS/MS |
liquid chromatography-electrospray ionization mass spectrometry |
LC-NMR |
liquid chromatography-nuclear magnetic resonance |
CE-MS |
capillary electrophoresis-mass spectrometry |
IL-6 |
interleuchine-6 |
TNF-α |
tumor necrosis factor-alpha |
SPT |
serine-palmitoyl transferase |
TLR-4 |
toll-like receptor 4 |
LPS |
lipopolysaccharides |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
JNK |
c-Jun N-terminal kinases |
SOCS |
suppressor of Cytokine Signaling |
SMPD |
sphingomyelin phosphodiesterase |
HFD |
high fat diet |
NAFLD |
non-alcoholic fatty liver disease |
T2DM |
type 2 diabetes mellitus |
HOMA-IR |
homeostatic Model Assessment for Insulin Resistance |
AST |
aspartate Aminotransferase |
ALT |
alanine aminotransferase |
LPC |
lysophosphatidylcholine |
SphK |
sphingosine kinase |
LacCer |
lactosylceramide |
dhSM |
dihydrosphingomyelin |
IR |
ischemia-reperfusion |
HIF1-α |
hypoxia inducible factor 1-α |