Table 7.
GO analysis of hub genes.
| Gene | GO Analysis [30] |
|---|---|
| SUGP1 | MF: nucleic acid binding; RNA binding; protein binding |
| BP: mRNA splicing, via spliceosome; RNA processing; mRNA processing; RNA splicing | |
| CC: nucleus; nucleoplasm; spliceosomal complex | |
| DHX16 | MF: nucleic acid binding; RNA binding; RNA helicase activity; helicase activity; protein binding |
| BP: mRNA splicing, via spliceosome; mRNA processing; RNA splicing | |
| CC: nucleus; nucleoplasm; spliceosomal complex; U2-type precatalytic spliceosome | |
| FUS | MF: nucleic acid binding; DNA binding; chromatin binding; transcription coactivator activity; RNA binding |
| BP: mRNA splicing, via spliceosome; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; RNA splicing; regulation of RNA splicing | |
| CC: nucleus; nucleoplasm; cytoplasm; polysome; dendrite | |
| HNRNPR | MF: nucleic acid binding; RNA binding; mRNA binding; mRNA 3’-UTR binding; protein binding |
| BP: nucleus; nucleoplasm; spliceosomal complex; NOT nucleolus; cytoplasm | |
| CC: mRNA splicing, via spliceosome; mRNA processing; circadian rhythm; RNA splicing; RNA metabolic process | |
| DHX15 | MF: nucleic acid binding; RNA binding; RNA helicase activity; double-stranded RNA binding; helicase activity |
| BP: mRNA splicing, via spliceosome; mRNA processing; RNA splicing; response to toxic substance; response to alkaloid | |
| CC: nucleus; nucleoplasm; U12-type spliceosomal complex; nucleolus; nuclear speck | |
| NAA38 | MF: protein binding |
| BP: negative regulation of apoptotic process | |
| CC: nucleus; cytoplasm; colocalizes_with polysome; NatC complex | |
| SKIV2L2 | MF: nucleic acid binding; RNA binding; RNA helicase activity; ATP-dependent RNA helicase activity; helicase activity |
| BP: RNA catabolic process; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; nuclear-transcribed mRNA catabolic process, 3’-5’ exonucleolytic nonsense-mediated decay | |
| CC: nucleus; cytoplasm; cytosol; Ski complex | |
| PLRG1 | MF: protein binding |
| BP: mRNA splicing, via spliceosome; mRNA processing; RNA splicing; protein localization to nucleus; positive regulation of G1/S transition of mitotic cell cycle | |
| CC: Prp19 complex; fibrillar center; nucleus; nucleoplasm; colocalizes_with DNA replication factor A complex |