Table 2.

Example of factors to consider in the evolution of vector-borne disease from the standpoint of the mosquito vector.

What the mosquito wants:

From the pathogen

1. Low pathogenicity to mosquito, not affect fitness

2. If it affects mosquito fitness, rapid passage through mosquito

From the vertebrate host (human)

1. High density of blood sources

2. Behave to be available to mosquito

3. Blood with sufficient nutrients to produce as many eggs as possible

4. Not harbor other pathogens that reduces mosquito fitness

5. Not develop technologies to lower mosquito fitness